How long does it take for CBD oil to work?


How long does it take for CBD to be effective?

Once you start consuming CBD you may wonder:

  • How long will it take for the non-intoxicating cannabinoid to take effect?
  • For how longs will its effects last?

To answer your confidence with resolute confidence, more clinical research is needed. However, you should first get a deep understanding of how CBD interacts with your body. 

How does CBD interact with your body?

Upon consuming CBD, it interacts with your brain via several distinct mechanisms which bring about a complex relationship. This relationship needs further research before one concludes how the cannabinoid can help.

Scientific reports show that CBD interacts with a broad range of proteins in your body and the Central Nervous System (CNS), once it enters your body. The most significant part of these interactions happens in the EndoCannabinoid System (ECS), more especially with the CB1 and CB2 receptors.

CBD has an inverse effect to THC, a highly intoxicating cannabinoid that also binds to the CB1 and CB2 receptors.

Once CBD is in the ECS, it helps prevent the absorption of anandamide, which is a natural cannabinoid that may help with relief.

Besides, CBD interacts with receptors that are not directly associated with the ECS. These receptors include vanilloid receptor TRPV1 and serotonin receptor 5-HT1A. The activation of such additional biological pathways could give rise to promising research on the pain-relieving and anti-inflammatory CBD properties.

Despite the relationship between CBD and the human body being rather complicated, it is easy to understand how the cannabinoid moves in your body and the times it takes to leave your system. Even this understanding is based on the method of consuming CBD, the quality and potency of the CBD, and the characteristics of the consumer.

How the method of consuming CBD matters.

The method one chooses to consume CBD can critically decide how long it will take for oneself to feel the cannabinoid’s effects. Some of the common methods of consuming CBD include:


One can consume CBD by administering several drops directly into his or her mouth. This method is most probably the quickest and easiest way to obtain CBD’s potential benefits. However, the quick swallowing of the CBD oil delays the entry of the cannabinoid into the bloodstream. Instead of entering directly, the cannabinoid has to go through the digestive tract and finally the liver, where it is broken down before entering the bloodstream.

Studies show that when the liver metabolizes CBD compounds, it undergoes “ the first pass effect”. This biological process involves the enzymes in the liver reducing CBD’s concentration before the remainder enters the bloodstream for circulation throughout the body.

The same principle applies to the ingestion of CBD edibles. For example, if you take CBD gummies or add some CBD oil to your recipe, the cannabinoid will ultimately go through the whole lengthy digestion process and the total concentration of CBD in the bloodstream will eventually reduce. Generally, when one consumes CBD via ingestion, it takes between one to two hours before he or she feels the effects.


You can also consume CBD sublingually by placing a few drops of CBD Oil under the tongue and swallowing. In this method, the mucous membrane, located in the mouth, absorbs the CBD. Therefore, it bypasses the digestive system and the liver.

When compared to ingestion, the sublingual method enables the consumer to do without the metabolization process, where CBD is broken in the liver. Consequently one can feel the CBD take effect faster when he or she uses the sublingual method.


The Inhalation method of consuming CBD involves smoking a high-CBD strain or taking a draw from a CBD vape pen. It is viewed as a very effective method of consuming CBD because of how fast the cannabidiol gets absorbed in the body.
When CBD is vaped or smoked, it is sent directly to the lungs where it directly enters the bloodstream and circulates throughout the body. Usually, the CBD reaches peak concentrations within three minutes after inhalation. As a result, you can feel the effects shortly after consuming the CBD.


The appropriate way to consume topical CBD is by applying it on the skin where it gets absorbed via the surface of the skin and binds to the localized cannabinoid receptors. Depending on the desired benefit, CBD-infused tropical should be applied in large amounts to get over the low absorption rate of cannabinoids via the skin.

Why the CBD dosage also matters

How CBD takes effect on the body also depends on some factors which vary from one consumer to the other. These factors include:


The amount of body fat in one’s body can influence the amount of CBD required to take effect. Someone having a larger body mass will require more CBD to feel its effects. Besides, body mass and weight influence how long CBD can remain in the system.

CBD, like THC, is stored in fat cells and is slowly removed from the body via urine and feces. CBD does not have to build up your system for it to work effectively. However, it can remain in the body even after its effects have diminished.


An individual’s metabolic rate also has some influence on how long CBD can stay in the system. Your body’s metabolic rate determines the time taken to break down and synthesize compounds. This factor affects how long it takes for the body to process and metabolize CBD.

Frequency of use

Apart from the body, the quality of the CBD product and the frequency of use also influence how long it can take for the cannabinoid to start working. Once you obtain CBD oil, your next step should be to determine your ideal dose, which includes the frequency of use.

Perhaps you have wondered about the perfect time to consume your CBD. Is it in the morning or at night? The answer to this question depends on several factors, including the type of CBD product and its potency.

A majority of reputable CBD product manufacturers provide instructions on the appropriate ways to use their products. Nevertheless, you may need experimentation to figure out the optimal CBD dose for your needs.

CBD dosage

Determining the perfect CBD dosage is a critical part of the process. Furthermore, it impacts how long CBD can stay in your system.

CBD products, sourced from hemp, are not meant to give the consumer an intoxicated feeling. Therefore, you do not have to be conservative with the dosage of these CBD products. However, you should begin with smaller doses and work your way up while monitoring the CBD effects.

How long does it take for your system to eliminate CBD?

The longevity of CBD in your system also depends on the previously mentioned factors, which determine the cannabinoid’s effectiveness.

According to a 2007 study, CBD can is detectable in one’s system for up to 72 hours after inhalation. Since it is the most effective method, one can use the inhalation method to get immediate relief. In another study, volunteers took cannabis extract soft-gelatin capsules that contained 1.35 mg of CBD and 1.45 mg of THC. The research team concluded that CBD is detectable in blood for up to six hours after ingestion.

One may be worried that consuming CBD can lead to him or her failing a drug test. However, it is least likely that CBD will show up on drug screenings as most drug tests focus on detecting THC and its metabolites.

Even CBD products sourced from hemp contain traces of THC. Although the chances are very slim, technically one can get a positive test result from consuming an unusually large dose of CBD(approximately 1000 to 2000 mg per day).

If you are worried about THC showing up in your system, you should look for broad-spectrum or CBD isolate products. Unlike full-spectrum oil, broad-spectrum and CBD isolate products are refined without the traces of THC that may be found in the profile of the hemp plant. CBD isolate products do not contain other cannabinoids apart from THC. They are the purest form of CBD available.

To obtain CBD of high quality, you should look for products that have a certificate of analysis from a certified third-party laboratory. You should also make certain that the information listed on the product’s label is accurate. Also, you should take caution not to obtain products claiming to be hemp seed oil or hemp oil as they rarely contain any CBD.

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